Semaglutide reconstitution calculator.
The original GLP-1 agonist — sold as Ozempic for type 2 diabetes and Wegovy for obesity. A 5 mg vial in 2 mL bacteriostatic water gives 2.5 mg/mL. Weekly subq injection, doses ramp from 0.25 mg to 2.4 mg.
★Semaglutide dose ranges between 0.25 mg to 2.4 mg (0.25–2.4 mg/week)
Draw the plunger to 40 units on a U-100 insulin syringe.
That’s 0.400 mL of solution, or 1 mg of peptide.
Reconstituting Semaglutide, step by step.
- 1Draw 2 mL of bacteriostatic water into a 3 mL syringe.
- 2Inject slowly down the side of the semaglutide vial — don't blast onto the powder.
- 3Swirl gently until clear. Do not shake.
- 4Refrigerate. Use within 4 weeks reconstituted.
Semaglutide questions, answered.
What's the standard semaglutide titration?+
0.25 mg/week for 4 weeks, then 0.5 mg, then 1 mg, then 1.7 mg, capping at 2.4 mg — step up every 4 weeks. The escalation isn't optional: jumping straight to high doses produces brutal GI side effects.
Semaglutide vs tirzepatide?+
Semaglutide is a pure GLP-1 agonist. Tirzepatide adds GIP agonism, producing more weight loss (18–22% vs. 12–15% in trials) with similar tolerability. Most people who plateau on semaglutide move to tirzepatide.
How much BAC water for a 5 mg semaglutide vial?+
2 mL is the convention. That gives you 2.5 mg/mL — 40 units (0.4 mL) on a U-100 syringe is 1 mg, a typical maintenance dose.
More for Semaglutide users.
Got the math. Now get the Semaglutide.
Eight peptide vendors, in the order we recommend. Our top pick is the one we actually order from.
See vendors →